Glass bottle with a glass stopper that is covered with a piece of leather with string wrapped round. White coloured powder inside. Printed label reads "Pelletier's Sulphate of Quinine". Second label has handwritten instructions "1 to 3 graines for a dose" and printed company name "Twinberrow, Dispensing Chemist, 2, Edwards Street, Portman Square." Pierre-Joseph Pelletier (22 March 1788 – 19 July 1842) was a French chemist who did notable research on vegetable alkaloids, and was the co-discoverer of quinine and strychnine. Pelletier's Sulphate of Quinine was sold under that name at least until 1869 (There is an advertisement for it in the New Orleans Commercial Bulletin of 27 June 1869) Quinine occurs naturally in the bark of the cinchona tree. The medicinal properties of the cinchona tree were originally discovered by the Quechua, who are indigenous to Peru and Bolivia; later, the Jesuits were the first to bring the cinchona to Europe. Savory 1836, p.73-4: “Quinine, Sulphate of. Is the name given to the newly discovered preparation derived from Peruvian bark, which contains all its active principles in a concentrated state, divested of extraneous matter; and the dose being consequentially small, it is likely to produce nausea or any derangement of stomach than bark in substance. It is often very desirable to administer this medicine in a small volume, and in an agreeable form. Patients often die of malignant fevers because they cannot swallow the necessary quantity of the bark in powder. (...) Chemistry, therefore, has done a great service to medicine by shewing how this separation may be accomplished beforehand. Sulphate of quinine is now generally prescribed in all cases where bark in substance has been usually given. (…)" (Goes on to describe use of quinine in tooth- and jawache)